E3 Ligand-Linker Conjugate 7( —— )

Catalog No. M13148 CAS No. 2022182-59-6

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Product Name

E3 Ligand-Linker Conjugate 7
Note

Research use only, not for human use.
Brief Description

An E3 ligase ligand-linker conjugate for PROTAC.
Description

An E3 ligase ligand-linker conjugate for PROTAC.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

——
Synonyms

——
Pathway

PROTACs
Target

E3 Ligase Ligand
Recptor

E3 Ligase Ligand
Research Area

Other Indications
Indication

——

CAS Number

2022182-59-6
Formula Weight

418.406
Molecular Formula

C19H22N4O7
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

N-(2-(2-aminoethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

1. Lohbeck J, et al. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5260-5262.

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